ScienceDaily for October 7, 2010 reported on iron and Alzheimer's.
Today it is clear that, under healthy conditions, iron and APP keep each other in check: If there's too much iron in a brain cell, more APP is made, and then APP and a partner molecule escort excess iron out. And, as the team reported last month in a related paper in the journal Cell, if there's too little iron, fewer APP molecules are made available to help escort iron out. As a result, iron accumulates, and the process begins again in a feedback loop.
